MATCHUP: Bears (1-0) at Panthers (1-0)
Noon Sunday TV/radio: WFLD-Ch. 32, WBBM-AM 780
Line: Panthers by 3
Weather: 92M-:, 30% chance of rain
THE BUZZ: Bears: After shocking Colts, they’ll need more than 150 passing yards from QB Kyle Orton to complement rookie RB Matt Forte.
Panthers: Were only 2-6 at home last year, but beating Chargers in San Diego sent Panthers home with momentum and confidence.
FANTASY OUTLOOK: Forte rushed for 123 yards and 5.3-yard average in opener. Panthers’ Jake Delhomme showed he’s back from elbow surgery, passing for 247 yards.
THE PICK: PANTHERS 21 BEARS 17
MATCHUP: Titans (1-0) at Bengals (0-1)
Noon Sunday
Line: Bengals by 1
Weather: 75M-:, 40% chance of rain
THE BUZZ: Titans: Kerry Collins moves into starting QB role with Vince Young out and will try to control tempo with short passes. Defense will keep Titans in many games.
Bengals: Offense looked terrible in loss to Ravens. Carson Palmer due for big game, and home opener would be good time.
FANTASY OUTLOOK: Titans RB Chris Johnson immediate weapon with 127 total yards in opener. Bengals’ Chad Ocho Cinco loves facing Titans (3 TDs in last meeting).
THE PICK: TITANS 21 BENGALS 17
MATCHUP: Packers (1-0) at Lions (0-1)
Noon Sunday
Line: Packers by 3
Weather: Dome
THE BUZZ: Packers: Aaron Rodgers did reasonable Brett Favre imitation in opener. Can he keep trend going? Packers have beaten Lions 7 of 8, 13 of 15, including both meetings last season.
Lions: Didn’t play run defense in loss to Falcons. Now it faces Ryan Grant, who picked up 101 yards, TD vs. Lions in December. No defense, no Lions win.
FANTASY OUTLOOK: Packers’ Donald Driver had 10 catches for 147 yards in last meeting. Lions’ Calvin Johnson had 7 catches in opener, matching career high vs. Pack in December.
THE PICK: PACKERS 23 LIONS 17
MATCHUP: Bills (1-0) at Jaguars (0-1)
Noon Sunday
Line: Jaguars by 5 1/2
Weather: Partly cloudy, 94M-:
THE BUZZ: Bills: QB Trent Edwards looked solid in win over Seahawks, but now Bills hit road against defense that will pressure him and stuff running game.
Jaguars: With injury problems, Jaguars will have to get creative on offense. Fred Taylor needs to find some running room.
FANTASY OUTLOOK: Bills WR Lee Evans had 4 catches for 102 yards in opener. Jaguars QB David Garrard will have to do more in passing game than last week’s 215 yards.
THE PICK: JAGUARS 20 BILLS 17
MATCHUP: Raiders (0-1) at Chiefs (0-1)
Noon Sunday
Line: Chiefs by 3 1/2
Weather: 66M-:, 30 percent chance of rain
THE BUZZ: Raiders: Looked like same old Raiders in blowout loss at home to Broncos. QB JaMarcus Russell will have to make big plays in passing game to win.
Chiefs: QB Damon Huard, who has won 8 of 12 as starter at home, takes over for Brodie Croyle.
FANTASY OUTLOOK: Raiders’ Justin Fargas gashed Chiefs for 139 yards in Nov. win. Chiefs’ Larry Johnson goes for 5th straight 100-yard game vs. Raiders.
THE PICK: CHIEFS 17 RAIDERS 16
MATCHUP: Colts (0-1) at Vikings (0-1)
Noon Sunday
TV: WBBM-Ch. 2
Line: Colts by 2
Weather: Dome
THE BUZZ: Colts: Loss to Bears showed Colts they’ll have to find new way to compensate for offensive line injuries. Confidence may be issue after surprising loss.
Vikings: Stud DTs Pat Williams and Kevin Williams should dominate, but will new DE Jared Allen show? If defense can’t dominate, Vikes are in trouble.
FANTASY OUTLOOK: Peyton Manning will keep looking to Reggie Wayne, who had 10 catches in opener. Vikings will try to control ball with RB Adrian Peterson.
THE PICK: VIKINGS 24 COLTS 20
MATCHUP: Giants (1-0) at Rams (0-1)
Noon Sunday
Line: Giants by 8 1/2
Weather: Dome
THE BUZZ: Giants: Putting that maybe-they’re-not-that-good talk to rest. Champs have won 10 straight road games and should be able to run and throw here.
Rams: 1-7 at home last season, didn’t show much life in blowout loss at Philly. RB Steven Jackson still fighting holdout rust.
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FANTASY OUTLOOK: Giants’ Brandon Jacobs may have second straight 100-yard game. Rams’ Marc Bulger threw for only 158 yards in opener; don’t look for much more.
THE PICK: GIANTS 27 RAMS 14
MATCHUP: Saints (1-0) at Redskins (0-1)
Noon Sunday
Line: Pick ’em
Weather: 90M-:, 30 percent chance of rain
THE BUZZ: Saints: If Reggie Bush can gain 163 total yards every week, Saints will be in playoffs. Drew Brees will have to spread ball around with Marques Colston out.
Redskins: Need catalyst on offense after scoring only one TD vs. Giants. Will it be QB Jason Campbell or WR Antwaan Randle El–or who?
FANTASY OUTLOOK: New Saints TE Jeremy Shockey had 6 catches in opener. Redskins RB Clinton Portis should find running room if passing game helps.
THE PICK: REDSKINS 24 SAINTS 20
MATCHUP: 49ers (0-1) at Seahawks (0-1)
3:05 p.m. Sunday
Line: Seahawks by 7
Weather: 75M-:, sunny
THE BUZZ: 49ers: All signs point to another long season for 49ers after opening with home loss to Cardinals. They need downfield passing game to take pressure off RB Frank Gore.
Seahawks: QB Matt Hasselbeck’s sore back among Seattle’s many ailments. Seattle needs this game to build momentum while key players heal.
FANTASY OUTLOOK: Gore has averaged 154 yards from scrimmage in last 4 games vs. Seahawks. RB Julius Jones should get plenty of work for Seahawks.
THE PICK: SEAHAWKS 27 49ERS 17
MATCHUP: Falcons (1-0) at Buccaneers (0-1)
3:05 p.m. Sunday
Line: Bucs by 7
Weather: 77M-:, cloudy
THE BUZZ: Falcons: Rookie QB Matt Ryan, new RB Michael Turner looked great in opening win. Was it just opponent (Lions), or will Atlanta be playoff contender?
Buccaneers: Staring at 0-2 start in division if they drop this one. They must stop run and get big game from fill-in QB Brian Griese.
FANTASY OUTLOOK: Turner’s 220-yard debut means he’s Falcon to stop until further notice. Bucs RB Earnest Graham averaged 9.1 yards per carry last week.
THE PICK: BUCS 27 FALCONS 23
MATCHUP: Dolphins (0-1) at Cardinals (1-0)
3:15 p.m. Sunday
Line: Cardinals by 6 1/2
Weather: Dome
THE BUZZ: Dolphins: Must find a way to run if they’re to pull upset. Cardinals can score, so keeping ball away from them is key.
Cardinals: Old-timers Kurt Warner and Edgerrin James should be able to keep it going against suspect Miami defense.
FANTASY OUTLOOK: New Dolphins tight end Anthony Fasano off to fast start with 8 catches. Cards’ Anquan Boldin also opened with 8 catches.
THE PICK: CARDINALS 28 DOLPHINS 17
MATCHUP: Chargers (0-1) at Broncos (1-0)
3:15 p.m. Sunday
Line: Chargers by 1 1/2
Weather: Partly cloudy, 68M-:
THE BUZZ: Chargers: Go to inhospitable venue trying to avoid 0-2 start that would dent Super Bowl hopes. But Chargers have won last 4 vs. Broncos by combined score of 147-53.
Broncos: Have won 8 straight home openers. Defense must do something it rarely does–contain LaDainian Tomlinson.
FANTASY OUTLOOK: Tomlinson has rushed for 7 TDs in last 4 vs. Broncos, gaining 100 yards 3 times. Broncos’ top WR, Brandon Marshall, back after 1-game suspension.
THE PICK: BRONCOS 24 CHARGERS 20
MATCHUP: Patriots (1-0) at Jets (1-0)
3:15 p.m. Sunday
TV: WBBM-Ch. 2
Line: Jets by 1 1/2
Weather: 84M-:, 30 percent chance of rain
THE BUZZ: Patriots: Matt Cassel will make 1st start since high school, but he has backed up some stud QBs. Patriots can’t ask him to do too much.
Jets: Brett Favre and new teammates smell major opportunity, though Pats’ defense can’t be taken lightly. Favre will have to move ball through air to open up run.
FANTASY OUTLOOK: RB Laurence Maroney rushed for 104 yards in last meeting. WR Jerricho Cotchery has 6 catches in last 4 vs. Pats and caught TD pass in opener.
THE PICK: JETS 24 PATRIOTS 20
MATCHUP: Steelers (1-0) at Browns (0-1)
7:15 p.m. Sunday
TV: WMAQ-Ch. 5
Line: Steelers by 6
Weather: 70M-:, 40 percent chance of rain
THE BUZZ: Steelers: Steelers have won last 9 meetings vs. their AFC North rivals. QB Ben Roethlisberger has thrown 10 TD passes in last 5 games vs. Browns.
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Browns: Browns embarrassed by Cowboys at home, and this won’t be much easier. It’s time for Browns to unwrap the offense, if they can.
FANTASY OUTLOOK: Willie Parker averaging 122.6 rushing yards vs. Browns, including 223-yard effort in ’06. Browns’ Braylon Edwards has 186 receiving yards in 2 games vs. Steelers.
THE PICK: STEELERS 27 BROWNS 20
MATCHUP: Ravens (1-0) at Texans (0-1)
7:30 p.m. Monday
Line: Texans by 4 1/2
Weather: Dome
THE BUZZ: Ravens: Rookie QB Joe Flacco takes step up in competition after opening win over Bengals. It would help if RB Willis McGahee can make it back from knee injury.
Texans: Texans struggling for answers on offense while relying on defense led by DE Mario Williams, who had 2 sacks in opener.
FANTASY OUTLOOK: Ravens WR Derrick Mason needs to make plays. Texans struggling to run, so Andre Johnson may need to repeat opening-day effort of 10 catches.
THE PICK: TEXANS 17 RAVENS 13
MATCHUP: Eagles (1-0) at Cowboys (1-0)
7:30 p.m. Monday
TV: ESPN
Line: Cowboys by 7
Weather: 70M-:, 20 percent chance of rain
THE BUZZ: Eagles: Donovan McNabb is healthy and Eagles are confident bunch. They have won last 2 visits to Dallas, but they’ll have to score lots to make it 3 in row.
Cowboys: Defense will have to come up with another big outing. Linebacker DeMarcus Ware has had a sack a game in last 4 vs. Eagles.
FANTASY OUTLOOK: Eagles rookie WR DeSean Jackson has 6 catches for 106 yards. Cowboys rookie RB Felix Jones may see more action after averaging 6.9 yards last week.
THE PICK: COWBOYS 30 EAGLES 27